RNA polymerase II

Preferred Label : RNA polymerase II;

MeSH definition : A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.;

MeSH synonym : dna-dependent rna polymerase ii; rna polymerase b; dna dependent rna polymerase ii; RNA pol II;

CISMeF synonym : b, rna polymerase; ii, rna polymerase; polymerase b, rna; polymerase ii, rna;

Registry Number MeSH : EC 2.7.7.-;

Is substance : O;

Details

Origin ID

D012319;

UMLS CUI

C0035679;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA-directed RNA Polymerase [NCIt concept]
- Deoxyribonucleic acid-directed ribonucleic acid polymerase (substance) [SNOMED CT concept]
- Nucleotidyltransferase [NCIt concept]
- RNA Polymerase [NCIt concept]
- transcription elongation regulator 1 [HGNC gene]
Currated CISMeF NLP mapping
- RNA Polymerase II [NCIt concept]
- Ribonucleic acid polymerase II (substance) [SNOMED CT concept]
Indexing information
- 9-beta-xylofuranosyladenine 5'-triphosphate [MeSH Supplementary Concept]
- RNA polymerase II-binding proteins [MeSH Supplementary Concept]
- Surb7 protein, mouse [MeSH Supplementary Concept]
- rpc19 protein, S pombe [MeSH Supplementary Concept]
Record concept(s)
- RNA polymerase II [MeSH concept]
Related MeSH Supplementary Concept(s)
- POLR2B protein, human [MeSH Supplementary Concept]
- POLR2C protein, human [MeSH Supplementary Concept]
- POLR2D protein, human [MeSH Supplementary Concept]
- POLR2F protein, human [MeSH Supplementary Concept]
- POLR2G protein, human [MeSH Supplementary Concept]
- POLR2J protein, human [MeSH Supplementary Concept]
- POLR2M protein, human [MeSH Supplementary Concept]
- Polr2m protein, mouse [MeSH Supplementary Concept]
- RNA polymerase II largest subunit [MeSH Supplementary Concept]
- RPB1 protein, S cerevisiae [MeSH Supplementary Concept]
- RPB11 protein, S cerevisiae [MeSH Supplementary Concept]
- RPB2 protein, S cerevisiae [MeSH Supplementary Concept]
- RPB3 protein, S cerevisiae [MeSH Supplementary Concept]
- RPB4 protein, S cerevisiae [MeSH Supplementary Concept]
- RPB4 protein, drosophila [MeSH Supplementary Concept]
- RPB7 protein, S cerevisiae [MeSH Supplementary Concept]
- RpII215 protein, Drosophila [MeSH Supplementary Concept]
- Rpb1 protein, S pombe [MeSH Supplementary Concept]
- Rpb1 protein, mouse [MeSH Supplementary Concept]
- Rpb7 protein, S pombe [MeSH Supplementary Concept]
- Rpb9 protein, S cerevisiae [MeSH Supplementary Concept]
- Rpb9 protein, S pombe [MeSH Supplementary Concept]
- rpb3 protein, S pombe [MeSH Supplementary Concept]
- rpb4 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RNA Polymerase II [NCIt concept]
- Ribonucleic acid polymerase II (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients