Poly(A) Polymerase Gamma

Preferred Label : Poly(A) Polymerase Gamma;

NCIt synonyms : PAPOLG; SRP RNA 3-Prime Adenylating Enzyme/PAP2; Nuclear Poly(A) Polymerase Gamma; PAP Gamma; PAP-Gamma; Neo-PAP; Neo-Poly(A) Polymerase; Polynucleotide Adenylyltransferase Gamma; SRP RNA 3' Adenylating Enzyme; EC 2.7.7.19; Signal Recognition Particle RNA-Adenylating Enzyme; SRP RNA-Adenylating Enzyme;

NCIt definition : Poly(A) polymerase gamma (736 aa, 83 kDa) is encoded by the human PAPOLG gene. This protein plays a role in RNA polyadenylation.;

NCIt note : Poly(A) polymerase gamma catalyzes template-independent extension of the 3 prime end of an RNA strand by nonspecific and CPSF/AAUAAA-dependent polyadenylation activity. (EntrezGene);

Details

Origin ID

C38951;

UMLS CUI

C1523975;

OMIM relation
- Poly(a) polymerase, gamma [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PAPOLG Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- RNA Polyadenylation [NCIt concept]
- RNA Synthesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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