Ribosomal Protein S6 Kinase Alpha-5

Preferred Label : Ribosomal Protein S6 Kinase Alpha-5;

NCIt synonyms : Ribosomal Protein-S6 Kinase Alpha-5; 90 kDa Ribosomal Protein S6 Kinase 5; Ribosomal Protein S6 Kinase 90kD Polypeptide 5; RPS6KA5; Mitogen- and Stress-Activated Protein Kinase 1; RSK-Like Protein Kinase; RSKL; Nuclear Mitogen- and Stress-Activated Protein Kinase-1; EC 2.7.11.1; Ribosomal Protein S6 Kinase Alpha 5; S6K-Alpha-5;

NCIt definition : Ribosomal protein S6 kinase alpha-5 (802 aa, 90 kDa) is encoded by the human RPS6KA5 gene. This protein is involved in signal transduction, histone phosphorylation and the activation of inflammatory gene expression.;

Details

Origin ID

C29909;

UMLS CUI

C0913240;

Currated CISMeF NLP mapping
- mitogen and stress-activated protein kinase 1 [MeSH concept]
- mitogen and stress-activated protein kinase 1 [MeSH Supplementary Concept]
OMIM relation
- Ribosomal protein s6 kinase a5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RPS6KA5 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- RPS6KA5 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bladder Cancer Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor 4 Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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