Diacylglycerol Kinase Zeta

Preferred Label : Diacylglycerol Kinase Zeta;

NCIt synonyms : DGK-Zeta; Diglyceride Kinase Zeta; DAG Kinase Zeta; EC 2.7.1.107;

NCIt definition : Diacylglycerol kinase zeta (1117 aa, 124 kDa) is encoded by the human DGKZ gene. This protein is involved in the phosphorylation of the second messenger molecule diacylglycerol.;

NCI Metathesaurus CUI : CL551942;

Details

Origin ID

C150102;

UMLS CUI

C4723715;

Automatic exact mappings (from CISMeF team)
- Diacylglycerol kinase, zeta, 104-kd: dgkz [OMIM gene]
- diacylglycerol kinase zeta [HGNC gene]
OMIM relation
- Diacylglycerol kinase, zeta, 104-kd: dgkz [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- DGKZ Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- DAG/PE-Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycerolipid Metabolism Pathway [NCIt concept]
- Glycerophospholipid Metabolism Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Negative Regulation of Mitosis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Diacylglycerol Kinase Zeta Inhibitor ASP1570 [NCIt concept]
- Diacylglycerol Kinase Zeta Inhibitor BAY2965501 [NCIt concept]
- Diacylglycerol Kinase Zeta Inhibitor BGB-30813 [NCIt concept]

Keyword's position in hierarchy(ies) :

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