Serine/Threonine-Protein Kinase ULK1

Preferred Label : Serine/Threonine-Protein Kinase ULK1;

NCIt synonyms : Unc-51-Like Kinase 1; Unc51-Like Kinase 1; EC 2.7.11.1; Autophagy-Related Protein 1 Homolog; ATG1; ATG1 Autophagy Related 1 Homolog; hATG1; ULK1;

NCIt definition : Serine/threonine-protein kinase ULK1 (1050 aa, 113 kDa) is encoded by the human ULK1 gene. This protein is involved in protein phosphorylation that mediates the autophagocytotic process.;

Details

Origin ID

C116614;

UMLS CUI

C1313678;

Automatic exact mappings (from CISMeF team)
- Autophagy-Related Protein-1 Homolog [MeSH concept]
- Autophagy-Related Protein-1 Homolog [MeSH Descriptor]
- Unc51-like autophagy-activating kinase 1 [OMIM gene]
OMIM relation
- Unc51-like autophagy-activating kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ULK1 protein, human [MeSH Supplementary Concept]
- ULK1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- ULK1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Autophagosome [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Autophagy Regulation Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- ULK1/2 Inhibitor DCC-3116 [NCIt concept]

Keyword's position in hierarchy(ies) :

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