NUAK Family SNF1-Like Kinase 1

Preferred Label : NUAK Family SNF1-Like Kinase 1;

NCIt synonyms : AMPK-Related Protein Kinase 5; EC 2.7.11.1; ARK5; AMP-Activated Protein Kinase Family Member 5; Omphalocele Kinase 1;

NCIt definition : NUAK family SNF1-like kinase 1 (661 aa, 74 kDa) is encoded by the human NUAK1 gene. This protein plays a role in protein phosphorylation, which regulates DNA damage response, apoptosis, cell adhesion, cellular senescence, and cell proliferation.;

Details

Origin ID

C126573;

UMLS CUI

C1173934;

Automatic exact mappings (from CISMeF team)
- NUAK family kinase 1 [HGNC gene]
- Nuak family, snf1-like kinase, 1 [OMIM gene]
OMIM relation
- Nuak family, snf1-like kinase, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NUAK1 protein, human [MeSH Supplementary Concept]
- NUAK1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NUAK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Narazaciclib [NCIt concept]

Keyword's position in hierarchy(ies) :

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