Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1

Preferred Label : Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1;

NCIt synonyms : BUB1 Budding Uninhibited by Benzimidazoles 1 Homolog (Yeast); BUB1; hBUB1; BUB1 Budding Uninhibited by Benzimidazoles 1 Homolog; EC 2.7.11.1; BUB1A; BUB1 Protein; Mitotic Spindle Checkpoint Kinase;

NCIt definition : Mitotic checkpoint serine/threonine-protein kinase BUB1 (1085 aa, 122 kDa) is encoded by the human BUB1 gene. This protein is involved in both protein phosphorylation and mitotic prometaphase.;

Details

Origin ID

C21495;

UMLS CUI

C3710678;

OMIM relation
- Bub1 mitotic checkpoint serine/threonine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- BUB1 protein, human [MeSH concept]
- BUB1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BUB1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Spleen [NCIt concept]
- Thymus Gland [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Cell Cycle Protein [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aurora B Signaling Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Colon Carcinoma [NCIt concept]
- Leukemia [NCIt concept]
- Lymphoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Mitotic Sister Chromatid Cohesion [NCIt concept]
- Mitotic/Spindle Checkpoint [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Prometaphase [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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