Mitotic Sister Chromatid Cohesion

Preferred Label : Mitotic Sister Chromatid Cohesion;

NCIt synonyms : Chromosome Cohesion;

NCIt definition : The faithful segregation of genetic information requires highly orchestrated changes of chromosome structure during the mitotic cell cycle. The linkage between duplicated sister DNAs is established during S phase and maintained throughout G2 phase (cohesion). In early mitosis, dramatic structural changes occur to produce metaphase chromosomes, each consisting of a pair of compacted sister chromatids (condensation). At anaphase onset, a signal is produced to disrupt the linkage between sister chromatids (separation), allowing them to be pulled apart to opposite poles of the cell. (from PubMed 10966455);

Details

Origin ID

C28752;

UMLS CUI

C1516543;

Currated CISMeF NLP mapping
- mitotic sister chromatid cohesion [GO term]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- mitotic sister chromatid cohesion [GO term]
biological_process_has_associated_location
- Cell [NCIt concept]
biological_process_has_initiator_chemical_or_drug
- Mitogen [NCIt concept]
biological_process_has_initiator_process
- Intercellular Communication Process [NCIt concept]
biological_process_involves_gene_product
- ATP-Dependent DNA Helicase DDX11 [NCIt concept]
- Chromosome Alignment-Maintaining Phosphoprotein 1 [NCIt concept]
- Cohesin Subunit SA-1 [NCIt concept]
- Cohesin Subunit SA-2 [NCIt concept]
- E3 SUMO-Protein Ligase NSE2 [NCIt concept]
- Kinesin-Like Protein KIF22 [NCIt concept]
- Kinetochore Scaffold 1 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 [NCIt concept]
- N-Acetyltransferase ESCO2 [NCIt concept]
- Pogo Transposable Element With ZNF Domain [NCIt concept]
- Shugoshin 1 [NCIt concept]
- Sister Chromatid Cohesion Protein PDS5 Homolog A [NCIt concept]
- Structural Maintenance of Chromosomes Protein 3 [NCIt concept]
- Wings Apart-Like Protein Homolog [NCIt concept]
biological_process_is_part_of_process
- Cell Cycle Process [NCIt concept]
- Cell Division Process [NCIt concept]
- Cell Proliferation [NCIt concept]
process_involves_gene
- BUB1 Gene [NCIt concept]
- BUB1 wt Allele [NCIt concept]
- CHAMP1 Gene [NCIt concept]
- CHAMP1 wt Allele [NCIt concept]
- DDX11 Gene [NCIt concept]
- DDX11 wt Allele [NCIt concept]
- ESCO2 Gene [NCIt concept]
- ESCO2 wt Allele [NCIt concept]
- KIF22 Gene [NCIt concept]
- KIF22 wt Allele [NCIt concept]
- KNL1 Gene [NCIt concept]
- KNL1 wt Allele [NCIt concept]
- NSMCE2 Gene [NCIt concept]
- NSMCE2 wt Allele [NCIt concept]
- NUF2 Gene [NCIt concept]
- NUF2 wt Allele [NCIt concept]
- PDS5A Gene [NCIt concept]
- PDS5A wt Allele [NCIt concept]
- POGZ Gene [NCIt concept]
- POGZ wt Allele [NCIt concept]
- SGO1 Gene [NCIt concept]
- SGO1 wt Allele [NCIt concept]
- SMC3 Gene [NCIt concept]
- SMC3 wt Allele [NCIt concept]
- STAG1 Gene [NCIt concept]
- STAG1 wt Allele [NCIt concept]
- STAG2 Gene [NCIt concept]
- STAG2 wt Allele [NCIt concept]
- WAPL Gene [NCIt concept]
- WAPL wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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