Preferred Label : NSMCE2 wt Allele;
NCIt synonyms : FLJ32440; C8orf36; MMS21; Zinc Finger, MIZ-Type Containing 7 Gene; NSE2; ZMIZ7; Methyl Methanesulfonate Sensitivity Gene 21; NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase wt Allele; MMS21, S. cerevisiae, Homolog of Gene; Chromosome 8 Open Reading Frame 36 Gene; Non-SMC Element 2 Homolog (MMS21, S. cerevisiae) Gene; Non-SMC Element 2, MMS21 Homolog (S. cerevisiae) Gene; Non-SMC Element 2, S. cerevisiae, Homolog of Gene;
NCIt definition : Human NSMCE2 wild-type allele is located in the vicinity of 8q24.13 and is approximately
275 kb in length. This allele, which encodes E3 SUMO-protein ligase NSE2 protein,
is involved in the negative regulation of apoptosis, protein sumoylation, and the
promotion of DNA repair. Mutation of the gene is associated with Seckel syndrome 10.;
NCI Metathesaurus CUI : CL514425;
GenBank Accession Number : AK057002;
Origin ID : C131564;
UMLS CUI : C4319722;
Automatic exact mappings (from CISMeF team)
- OMIM relation
- Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
