Telomere Recombination

Preferred Label : Telomere Recombination;

NCIt synonyms : Telomere-Telomere Recombination;

NCIt definition : Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical on all telomeres in a given species. The 3-prime end of one chromosome can invade a second chromosome and use the sequence of the second chromosome as a template for telomere elongation by DNA polymerase. The lagging strand can then be filled in by conventional replication mechanisms.;

Details

Origin ID

C20340;

UMLS CUI

C1515262;

Semantic type(s)
- Genetic Function [UMLS semantic type]
biological_process_has_associated_location
- Telomere [NCIt concept]
biological_process_involves_gene_product
- E3 SUMO-Protein Ligase NSE2 [NCIt concept]
- Flap Endonuclease 1 [NCIt concept]
biological_process_is_part_of_process
- Cell Survival [NCIt concept]
process_involves_gene
- FEN1 Gene [NCIt concept]
- FEN1 wt Allele [NCIt concept]
- NSMCE2 Gene [NCIt concept]
- NSMCE2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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