Preferred Label : Leukemia;
NCIt synonyms : Blood (Leukemia);
NCIt related terms : Leukemia NOS; Leukemia, Disease; Leukemia, NOS; Leukemias; LEUKEMIA, MALIGNANT; Leukemias, General;
NCIt definition : A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and
characterized by the presence of primitive or atypical myeloid or lymphoid cells in
the bone marrow and the blood. Leukemias are classified as acute or chronic based
on the degree of cellular differentiation and the predominant cell type present. Leukemia
is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly.
Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute
lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia.
Treatment is vital to patient survival; untreated, the natural course of acute leukemias
is normally measured in weeks or months, while that of chronic leukemias is more often
measured in months or years.;
Alternative definition : NCI-GLOSS: Cancer that starts in blood-forming tissue such as the bone marrow and
causes large numbers of blood cells to be produced and enter the bloodstream.; CDISC: A progressive, proliferative disease of blood cells, originating from myeloid
or lymphoid stem cells.; NICHD: A cancer of the blood or bone marrow that is characterized by increased production
of abnormal blood cells.;
Neoplastic status : Malignant;
ICD-O code : 9800/3;
Codes from synonyms : 10024312; CDR0000045343;
Origin ID : C3161;
UMLS CUI : C0023418;
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- leukemia [Blood Transfusion thesaurus concept]
- DO Cross reference
- False automatic mappings
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- associated_with_malfunction_of_gene_product
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_associated_gene
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- may_be_associated_disease_of_disease