FOXO4 wt Allele

Preferred Label : FOXO4 wt Allele;

NCIt synonyms : AFX1; MGC120490; MLLT7; FOXO4; Forkhead Box O4 wt Allele; AFX; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 7 Gene; ALL1-Fused Gene from X Chromosome; MLLT7 wt Allele; Mixed Lineage Leukemia, Translocated to, 7 Gene; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated to, 7 Gene;

NCIt definition : Human FOXO4 wild-type allele is located in the vicinity of Xq13.1 and is approximately 7 kb in length. This allele, which encodes forkhead box protein O4, plays a role in the modulation of transcription by RNA polymerase II. Acute nonlymphocytic leukemias and T-cell acute lymphocytic leukemias are associated with translocations t(X;11)(q13;q23) of the gene to the MLL gene.;

GenBank Accession Number : NM_005938;

Details

Origin ID

C53081;

UMLS CUI

C1704966;

OMIM relation
- Forkhead box o4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- Xq13.1 [NCIt concept]
gene_is_element_in_pathway
- AKT Signaling Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- HDAC Class III Signaling Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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