AXL wt Allele - CISMeF

Preferred Label : AXL wt Allele;

NCIt synonyms : AXL Receptor Tyrosine Kinase wt Allele; AXL Transforming Gene; UFO Gene; ARK; JTK11; Tyro7; AXL Transforming Sequence/Gene;

NCIt definition : Human AXL wild-type allele is located in the vicinity of 19q13.2 and is approximately 43 kb in length. This allele, which encodes tyrosine-protein kinase receptor UFO protein is involved in extracellular matrix signal transduction and cellular proliferation stimulation. The AXL gene is a chronic myelogenous leukemia-associated oncogene and is also associated with colon cancer and melanoma.;

GenBank Accession Number : NM_001699;

Details

Origin ID

C51739;

UMLS CUI

C1705718;

Automatic exact mappings (from CISMeF team)
- Axl receptor tyrosine kinase [OMIM gene]
- Shark [LOINC component]
- sharks [MeSH Descriptor]
OMIM relation
- Axl receptor tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 19: 46416663-46459511 [NCIt concept]
gene_in_chromosomal_location
- 19q13.1 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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