Preferred Label : AFDN wt Allele;
NCIt synonyms : AF-6; AFADIN; FLJ34371; AF6; RP3-431P23.3; MLLT4; CANOE, Drosophila, Homolog of Gene; Myeloid/Lymphoid or Mixed-Lineage Leukemia, Translocated to, 4 Gene; l-afadin; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated
to, 4 Gene; Afadin, Adherens Junction Formation Factor wt Allele; ALL1-Fused Gene From Chromosome 6; MLLT4 wt Allele; Mixed-Lineage Leukemia, Translocated to, 4 Gene;
NCIt definition : Human AFDN wild-type allele is located in the vicinity of 6q27 and is approximately
145 kb in length. This allele, which encodes afadin protein, is involved in the mediation
of cell to cell adhesion. The gene can be involved in a translocation with the KMT2A
(MLL) gene, t(6;11)(q27;q23), which is associated with some acute leukemias.;
GenBank Accession Number : NM_005936;
Origin ID : C54315;
UMLS CUI : C1706479;
Currated CISMeF NLP mapping
- afadin [MeSH Supplementary Concept]
- OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_associated_with_disease
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_is_element_in_pathway
- gene_plays_role_in_process
