Serine/Threonine-Protein Kinase Nek2

Preferred Label : Serine/Threonine-Protein Kinase Nek2;

NCIt synonyms : Never In Mitosis A-Related Kinase 2; EC 2.7.11.1; HsPK 21; NimA-Like Protein Kinase 1; NimA-Related Protein Kinase 2; NIMA-Related Kinase 2;

NCIt definition : Serine/threonine-protein kinase Nek2 (445 aa, 52 kDa) is encoded by the human NEK2 gene. This protein plays a role in chromosome dynamics during cell division.;

Details

Origin ID

C138106;

UMLS CUI

C1505136;

Automatic exact mappings (from CISMeF team)
- NIMA related kinase 2 [ORDO Gene]
- NIMA related kinase 2 [HGNC gene]
- Nima-related kinase 2 [OMIM gene]
OMIM relation
- Nima-related kinase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NEK2 protein, human [MeSH Supplementary Concept]
- NEK2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NEK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centrosome [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine Zipper [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromosome Condensation [NCIt concept]
- Mitotic Chromosomal Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Hec1/Nek2 Inhibitor T-1101 Tosylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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