Leucine Zipper

Preferred Label : Leucine Zipper;

NCIt definition : Domains in DNA-binding proteins that contain amino acid sequences that show periodic arrays of leucine residues. These residues exist in an alpha-helical conformation, with the leucine side chains extending from one alpha helix interdigitating with those displayed from a similar alpha helix of a second polypeptide, facilitating dimerization.;

Details

Origin ID

C13291;

UMLS CUI

C0079686;

Currated CISMeF NLP mapping
- leucine zippers [MeSH Descriptor]
- leucine zippers [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- leucine zippers [MeSH concept]
- leucine zippers [MeSH Descriptor]
is_structural_domain_or_motif_of_gene_product
- Cyclic AMP-Dependent Transcription Factor ATF-1 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-2 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-3 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-4 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-5 [NCIt concept]
- Cyclic AMP-Dependent Transcription Factor ATF-6 Alpha [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 1 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 3 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 1 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 3 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 4 [NCIt concept]
- Cyclic AMP-Responsive Element-Binding Protein 5 [NCIt concept]
- Fanconi Anemia Group G Protein [NCIt concept]
- Forkhead Box Protein P4 [NCIt concept]
- Leucine Zipper Putative Tumor Suppressor 1 [NCIt concept]
- PRKC Apoptosis WT1 Regulator Protein [NCIt concept]
- Protein Max [NCIt concept]
- Serine/Threonine-Protein Kinase Nek2 [NCIt concept]
- Sister Chromatid Cohesion Protein PDS5 Homolog B [NCIt concept]
- Transcription Factor EB [NCIt concept]
- cAMP Responsive Element Binding Protein [NCIt concept]
- cAMP-Responsive Element Modulator [NCIt concept]
- cAMP-Responsive Element-Binding Protein-Like 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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