Cyclic AMP-Dependent Transcription Factor ATF-1

Preferred Label : Cyclic AMP-Dependent Transcription Factor ATF-1;

NCIt synonyms : cAMP-Dependent Transcription Factor ATF-1; Activating Transcription Factor 1; Protein TREB36; ATF1; ATF-1;

NCIt definition : Cyclic AMP-dependent transcription factor ATF-1 (271 aa, 29 kDa) is encoded by the human ATF1 gene. This protein is involved in the regulation of transcription.;

NCIt note : Cyclic AMP-dependent transcription factor ATF-1 binds the cAMP response element (CRE) that has a consensus sequence 5'-GTGACGT(AC)(AG)-3'. (UniProt);

Details

Origin ID

C92179;

UMLS CUI

C2984895;

Currated CISMeF NLP mapping
- activating transcription factor 1 [MeSH Descriptor]
- activating transcription factor 1 [MeSH concept]
OMIM relation
- Activating transcription factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ATF1 Gene [NCIt concept]
- CREB Family Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- Leucine Zipper [NCIt concept]
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Angiomatoid Fibrous Histiocytoma [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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