" /> Cyclic AMP-Responsive Element-Binding Protein 1 - CISMeF





Preferred Label : Cyclic AMP-Responsive Element-Binding Protein 1;

NCIt synonyms : cAMP-Responsive Element Binding Protein 1; CREB-1; cAMP Responsive Element Binding Protein 1; CREB1; Active Transcription Factor CREB; Transactivator Protein; cAMP Responsive Element Binding Protein-1;

NCIt definition : Cyclic AMP-responsive element-binding protein 1 (341 aa, 37 kDa) is encoded by the human CREB1 gene. This protein plays a role in transcriptional regulation.;

NCIt note : cAMP Responsive Element Binding Protein 1 is a homodimeric transcription factor containing 1 KID domain, phosphorylated/stimulated by several protein kinases, that binds to octameric DNA palindrome cAMP-response elements (CRE) present in many viral and cellular promoters and induces gene transcription in response to hormonal stimulation of the cAMP pathway.;

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30/07/2025


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