Leucine Zipper Putative Tumor Suppressor 1

Preferred Label : Leucine Zipper Putative Tumor Suppressor 1;

NCIt synonyms : F37/Esophageal Cancer-Related Gene-Coding Leucine-Zipper Motif; Fez1; LZTS1;

NCIt definition : Leucine zipper putative tumor suppressor 1 (596 aa, 67 kDa) is encoded by the human LZTS1 gene. This protein plays a role in tumor suppression, cell cycle modulation, cell growth control and transcriptional regulation.;

Details

Origin ID

C118979;

UMLS CUI

C1309037;

Automatic exact mappings (from CISMeF team)
- Fasciculation and elongation protein zeta 1 [OMIM gene]
- Leucine zipper, putative tumor suppressor 1 [OMIM gene]
- leucine zipper tumor suppressor 1 [HGNC gene]
OMIM relation
- Leucine zipper, putative tumor suppressor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LZTS1 protein, human [MeSH Supplementary Concept]
- LZTS1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LZTS1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- Tumor Suppressor Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Leucine Zipper [NCIt concept]
gene_product_plays_role_in_biological_process
- Transcription Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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