Sister Chromatid Cohesion Protein PDS5 Homolog B

Preferred Label : Sister Chromatid Cohesion Protein PDS5 Homolog B;

NCIt synonyms : APRIN; Androgen-Induced Proliferation Inhibitor; Androgen-Induced Prostate Proliferative Shutoff Associated Protein; Androgen-Induced Prostate Proliferative Shutoff-Associated Protein AS3; APRIN Protein; PDS5BB; Androgen-Induced Prostate Proliferative Shutoff-Associated Protein;

NCIt definition : Sister chromatid cohesion protein PDS5 homolog B (1447 aa, 165 kDa) is encoded by the human PDS5B gene. This protein plays a role in the regulation of both mitosis and cell proliferation.;

NCIt note : Putative regulator of androgen-induced proliferative prostate cell arrest; may interact with other proteins and bind DNA; contains leucine-zipper, DNA- and ATP-binding motifs. (LocusLink);

Details

Origin ID

C21332;

UMLS CUI

C1332106;

OMIM relation
- Pds5 cohesin-associated factor b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- PDS5B Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- DNA Binding Domain [NCIt concept]
- Leucine Zipper [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Epithelial Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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