cAMP-Responsive Element Modulator

Preferred Label : cAMP-Responsive Element Modulator;

NCIt synonyms : Inducible cAMP Early Repressor ICER; CREM; Inducible cAMP Early Repressor; ICER; cAMP Response Element Modulator;

NCIt definition : cAMP-responsive element modulator (345 aa, 37 kDa) is encoded by the human CREM gene. This protein plays a role in the regulation of gene expression.;

NCIt note : Some isoforms of cAMP-responsive element modulator are transcriptional activators and other isoforms are transcriptional repressors.;

Details

Origin ID

C162405;

UMLS CUI

C5202704;

Automatic exact mappings (from CISMeF team)
- Camp response element modulator [OMIM gene]
- cAMP responsive element modulator [HGNC gene]
- cremation [MeSH Descriptor]
- cyclic amp response element modulator [MeSH Descriptor]
- ointments [MeSH Descriptor]
OMIM relation
- Camp response element modulator [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- CREB Family Gene [NCIt concept]
- CREM Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Testis [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
- Spermatid [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine Zipper [NCIt concept]
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Pain Repression Pathway [NCIt concept]
- Spermatogenesis Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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