Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2

Preferred Label : Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2;

NCIt synonyms : BBF2 Human Homolog On Chromosome 7; cAMP-Responsive Element-Binding Protein 3-Like Protein 2; CREB3L2;

NCIt definition : Cyclic AMP-responsive element-binding protein 3-like protein 2 (520 aa, 57 kDa) is encoded by the human CREB3L2 gene. This protein is involved in the mediation of gene expression.;

NCIt note : Cyclic AMP-responsive element-binding protein 3-like protein 2 is found in the membrane of the endoplasmic reticulum. Stress of this organelle causes cleavage of the protein. This releases the N-terminal cytoplasmic domain which then translocates into the nucleus. (UniProt);

Details

Origin ID

C95482;

UMLS CUI

C2987178;

OMIM relation
- Camp response element-binding protein 3-like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CREB Family Gene [NCIt concept]
- CREB3L2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine Zipper [NCIt concept]
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- Huntington's Disease Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Vasopressin-Regulated Water Reabsorption Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Low Grade Fibromyxoid Sarcoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Stress Response [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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