Serine/Threonine-Protein Kinase Sgk1

Preferred Label : Serine/Threonine-Protein Kinase Sgk1;

NCIt synonyms : EC 2.7.11.1; Serum/Glucocorticoid-Regulated Kinase 1; Serine/Threonine-Protein Kinase Sgk;

NCIt definition : Serine/threonine-protein kinase Sgk1 (431 aa, 49 kDa) is encoded by the human SGK1 gene. This protein plays a role in both signaling in response to cellular stress and serine/threonine phosphorylation.;

Details

Origin ID

C101561;

UMLS CUI

C1528301;

Automatic exact mappings (from CISMeF team)
- Serum/glucocorticoid-regulated kinase 1 [OMIM gene]
OMIM relation
- Serum/glucocorticoid-regulated kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- SGK1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SGK1 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Class I PI3K Signaling Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- Insulin Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth Regulation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Regulation of Cell Death Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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