Cyclin-Dependent Kinase 12

Preferred Label : Cyclin-Dependent Kinase 12;

NCIt synonyms : Cell Division Protein Kinase 12; Cdc2-Related Kinase, Arginine/Serine-Rich; CDC2-Related Protein Kinase 7; EC 2.7.11.22; CrkRS; EC 2.7.11.23; hCDK12; Cell Division Cycle 2-Related Protein Kinase 7; Cdc2-Related Kinase with an Arginine/Serine-Rich Domain;

NCIt definition : Cyclin-dependent kinase 12 (1490 aa, 164 kDa) is encoded by the human CDK12 gene. This protein is involved in the regulation of both RNA splicing and transcription elongation through the mediation of serine/threonine phosphorylation.;

Details

Origin ID

C101097;

UMLS CUI

C1620114;

OMIM relation
- Cyclin-dependent kinase 12 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CDK12 protein, human [MeSH concept]
- CDK12 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDK12 Gene [NCIt concept]
- Cell Cycle Gene [NCIt concept]
- Cyclin-Dependent Kinase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- RNA Splicing [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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