DNA-Directed RNA Polymerase II Subunit RPB1

Preferred Label : DNA-Directed RNA Polymerase II Subunit RPB1;

NCIt synonyms : hsRPB1; RPOL2; RPB1; RPO2; RpIILS; RPBh1; POLR2; hRPB220; DNA-Directed RNA Polymerase II Largest Subunit; Polymerase (RNA) II (DNA Directed) Polypeptide A (220kD); POLRA; RNA Polymerase II 220 kD Subunit; POLR2A; Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa; DNA-Directed RNA Polymerase II Subunit A; RNA-Directed RNA Polymerase II Subunit RPB1; EC 2.7.7.6; EC 2.7.7.48; RNA Polymerase II Subunit B1; DNA Directed RNA Polymerase II Polypeptide A; DNA-Directed RNA Polymerase-II Polypeptide-A;

NCIt definition : DNA-directed RNA polymerase II subunit RPB1 (1970 aa, 217 kDa) is encoded by the human POLR2A gene. This protein is involved in RNA metabolism, transcription and excision repair.;

Details

Origin ID

C34071;

UMLS CUI

C1333229;

OMIM relation
- Polymerase II, rna, subunit a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- POLR2A Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- IFN-Beta Enhancer Pathway [NCIt concept]
- Pain Repression Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
- RNA Polymerase Assembly Pathway [NCIt concept]
- Telomere Pathway [NCIt concept]
- hSWI-SNF Pathway [NCIt concept]
gene_product_is_physical_part_of
- RNA Polymerase II [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- RNA Processing [NCIt concept]
- RNA Synthesis [NCIt concept]
- Transcription [NCIt concept]
- Transcription Elongation [NCIt concept]

Keyword's position in hierarchy(ies) :

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