Integrin-Linked Protein Kinase

Preferred Label : Integrin-Linked Protein Kinase;

NCIt synonyms : ILK; p59ILK; 59 kDa Serine/Threonine-Protein Kinase; ILK-2; Integrin-Linked Kinase; EC 2.7.11.1; ILK-1; Epididymis Secretory Protein Li 28;

NCIt definition : Integrin-linked protein kinase (452 aa, 51 kDa) is encoded by the human ILK gene. This protein plays a role in the regulation of integrin-mediated signaling.;

NCIt note : Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta integrins.;

Details

Origin ID

C26290;

UMLS CUI

C1999806;

Automatic exact mappings (from CISMeF team)
- Integrin-linked kinase [OMIM gene]
Currated CISMeF NLP mapping
- integrin-linked kinase [MeSH concept]
- integrin-linked kinase [MeSH Supplementary Concept]
OMIM relation
- Integrin-linked kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ILK protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- ILK Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- PTEN-Dependent Cell Cycle Arrest and Apoptosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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