Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4

Preferred Label : Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4;

NCIt synonyms : GCN2 EIF2alpha Kinase; EC 2.7.11.1; GCN2-Like Protein; eIF-2-Alpha Kinase GCN2;

NCIt definition : Eukaryotic translation initiation factor 2-alpha kinase 4 (1649 aa, 187 kDa) is encoded by the human EIF2AK4 gene. This protein plays a role in both translational regulation and protein phosphorylation.;

Details

Origin ID

C113597;

UMLS CUI

C2354171;

Automatic exact mappings (from CISMeF team)
- Eukaryotic translation initiation factor 2-alpha kinase 4 [OMIM gene]
OMIM relation
- Eukaryotic translation initiation factor 2-alpha kinase 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- EIF2AK4 protein, human [MeSH Supplementary Concept]
- EIF2AK4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EIF2AK4 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Translation Process Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Translational Repression [NCIt concept]
is_target
- GCN2 Modulator HC-7366-K [NCIt concept]

Keyword's position in hierarchy(ies) :

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