Glycogen Synthase Kinase-3 Beta

Preferred Label : Glycogen Synthase Kinase-3 Beta;

NCIt synonyms : Glycogen Synthase Kinase 3-Beta; GSK3B; Serine/Threonine-Protein Kinase GSK3B; EC 2.7.11.1; EC 2.7.11.26; GSK3-beta; GSK-3 Beta;

NCIt definition : Glycogen synthase kinase-3 beta (420 aa, 47 kDa) is encoded by the human GSK3B gene. This protein plays a role in both protein phosphorylation and the inhibition of glycogen synthesis.;

Details

Origin ID

C128886;

UMLS CUI

C4308090;

Automatic exact mappings (from CISMeF team)
- Glycogen Synthase Kinase 3 beta [MeSH Descriptor]
- Glycogen synthase kinase 3-beta [OMIM gene]
- glycogen synthase kinase 3 beta [MeSH concept]
OMIM relation
- Glycogen synthase kinase 3-beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GSK3B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GSK3B Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Glycogen Synthase Kinase 3 [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- ALK Pathway [NCIt concept]
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- G1/S Checkpoint Pathway [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Notch and Wnt Signaling Pathway [NCIt concept]
- Phosphoinositide Pathway [NCIt concept]
- Pitx2 Transcription Regulation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- Skeletal Muscle Hypertrophy Pathway [NCIt concept]
- Sonic Hedgehog Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- eIF2 Regulation Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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