Glycogen Synthase Kinase 3 beta

Preferred Label : Glycogen Synthase Kinase 3 beta;

MeSH definition : A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.;

MeSH synonym : GSK-3beta; GSK 3beta; GSK3beta; GSK3B Protein;

Registry Number MeSH : EC 2.7.11.1;

Wikipedia link : https://en.wikipedia.org/wiki/Glycogen synthase kinase 3 beta;

UNII : EC 2.7.11.1;

Details

Origin ID

D000071679;

UMLS CUI

C0244988;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- GSK3B Gene [NCIt concept]
- Glycogen Synthase Kinase-3 Beta [NCIt concept]
- glycogen synthase kinase 3 beta [HGNC gene]
Record concept(s)
- glycogen synthase kinase 3 beta [MeSH concept]
Related MeSH Supplementary Concept(s)
- GSK3B protein, human [MeSH Supplementary Concept]
- Gsk3b protein, mouse [MeSH Supplementary Concept]
- Gsk3b protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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