[Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2, Mitochondrial

Preferred Label : [Pyruvate Dehydrogenase (Acetyl-Transferring)] Kinase Isozyme 2, Mitochondrial;

NCIt synonyms : PDKII; EC 2.7.11.2; PDK2; PDH Kinase 2; Pyruvate Dehydrogenase Kinase Isoform 2;

NCIt definition : [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (407 aa, 46 kDa) is encoded by the human PDK2 gene. This protein plays a role in serine/threonine phosphorylation of pyruvate dehydrogenase.;

NCI Metathesaurus CUI : CL982460;

Details

Origin ID

C179160;

UMLS CUI

C2000206;

Automatic exact mappings (from CISMeF team)
- Pyruvate dehydrogenase kinase, isoenzyme 2 [OMIM gene]
- pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO term]
OMIM relation
- Pyruvate dehydrogenase kinase, isoenzyme 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PDK2 protein, human [MeSH Supplementary Concept]
- PDK2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PDK2 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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