Eukaryotic Elongation Factor 2 Kinase

Preferred Label : Eukaryotic Elongation Factor 2 Kinase;

NCIt synonyms : Calcium/Calmodulin-Dependent Eukaryotic Elongation Factor 2 Kinase; EC 2.7.11.20; EEF-2 Kinase; Calcium/Calmodulin-Dependent Eukaryotic Elongation Factor-2 Kinase; eEF-2K; Elongation Factor-2 Kinase; Calmodulin-Dependent Protein Kinase III;

NCIt definition : Eukaryotic elongation factor 2 kinase (725 aa, 82 kDa) is encoded by the human EEF2K gene. This protein is involved in both the negative regulation of protein synthesis and serine/threonine protein phosphorylation.;

Details

Origin ID

C119728;

UMLS CUI

C1870461;

Automatic exact mappings (from CISMeF team)
- Eukaryotic elongation factor 2 kinase [OMIM gene]
- elongation factor 2 kinase [MeSH concept]
- elongation factor 2 kinase [MeSH Descriptor]
- elongation factor-2 kinase activity [GO term]
- eukaryotic elongation factor 2 kinase [HGNC gene]
OMIM relation
- Eukaryotic elongation factor 2 kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- EEF2K protein, human [MeSH Supplementary Concept]
- EEF2K protein, human [MeSH concept]
gene_encodes_gene_product
- EEF2K Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Calcium Binding Protein [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Protein Translation Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
- p38-gamma and p38-delta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Translational Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients