Serine/Threonine-Protein Kinase PLK2

Preferred Label : Serine/Threonine-Protein Kinase PLK2;

NCIt synonyms : Serine/Threonine-Protein Kinase SNK; SNK; hSNK; EC 2.7.11.21; hPlk2; PLK-2; Polo-Like Kinase 2; Serum-Inducible Kinase;

NCIt definition : Serine/threonine-protein kinase PLK2 (685 aa, 78 kDa) is encoded by the human PLK2 gene. This protein is involved in cell cycle progression, centriole duplication and serine/threonine phosphorylation.;

Details

Origin ID

C29991;

UMLS CUI

C1565490;

Currated CISMeF NLP mapping
- serum-inducible kinase [MeSH concept]
- serum-inducible kinase [MeSH Supplementary Concept]
OMIM relation
- Polo-like kinase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLK2 protein, human [MeSH concept]
- PLK2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PLK2 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centriole [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Polo-Box Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- PLK2 and PLK4 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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