Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

Preferred Label : Matrix-Assisted Laser Desorption Ionization Mass Spectrometry;

NCIt synonyms : MALDI; Matrix Assisted Laser Desorption Ionization Mass Spectrometry;

Alternative definition : CDISC: A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample- matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. (CHI);

Details

Origin ID

C48040;

UMLS CUI

C0282597;

Currated CISMeF NLP mapping
- spectrometry, mass, Matrix-Assisted laser Desorption-Ionization [MeSH concept]
- spectrometry, mass, matrix-assisted laser desorption-ionization [MeSH Descriptor]
Semantic type(s)
- Laboratory Procedure [UMLS semantic type]
UMLS correspondences (same concept)
- MS.MALDI [LOINC method]
- spectrometry, mass, Matrix-Assisted laser Desorption-Ionization [MeSH concept]
- spectrometry, mass, matrix-assisted laser desorption-ionization [MeSH Descriptor]
concept_is_in_subset
- CDISC SDTM Method Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CTRP Intervention Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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