LIM Domain Kinase 1

Preferred Label : LIM Domain Kinase 1;

NCIt synonyms : LIMK1; LIMK-1; LIM KINASE; EC 2.7.1.37; EC 2.7.11.1; LIM Domain Kinase-1;

NCIt definition : LIM domain kinase 1 (647 aa, 73 kDa) is encoded by the human LIMK1 gene. This protein is involved in both actin cytoskeleton organization and serine/threonine phosphorylation.;

Details

Origin ID

C29922;

UMLS CUI

C0294273;

Currated CISMeF NLP mapping
- lim kinases [MeSH Descriptor]
- lim kinases [MeSH concept]
OMIM relation
- Lim domain kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LIMK1 protein, human [MeSH concept]
- LIMK1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- LIMK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- LIM Domain [NCIt concept]
- PDZ Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- CCR3 Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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