Preferred Label : LIM Domain;
NCIt synonyms : CRR Domain; Cysteine Rich Region;
NCIt definition : The LIM domain is a zinc binding, cysteine rich motif consisting of two tandemly repeated
zinc fingers. Unlike GATA type zinc fingers, LIM domains do not bind DNA but instead
mediate protein-protein interactions. Functionally, LIM domain containing proteins
have been implicated in cell lineage specification, cytoskeletal organization, and
organ development.;
Origin ID : C13672;
UMLS CUI : C1517692;
Semantic type(s)
is_structural_domain_or_motif_of_gene_product