LIM Domain-Binding Protein 3

Preferred Label : LIM Domain-Binding Protein 3;

NCIt synonyms : Z-Band Alternatively Spliced PDZ-Motif Protein; Protein Cypher; Z-Band Alternatively Spliced PDZ Motif-Containing Protein; Z-Band Alternatively Spliced PDZ Motif Protein; LDB3;

NCIt definition : LIM domain-binding protein 3 (727 aa, 77 kDa) is encoded by the human LDB3 gene. This protein is involved in sarcomere maintenance and the localization of protein kinase C to the cytoskeleton through binding to both alpha-actinin-2 and protein kinase C.;

Details

Origin ID

C202910;

UMLS CUI

C1312915;

OMIM relation
- Lim domain-binding 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LDB3 protein, human [MeSH Supplementary Concept]
- LDB3 protein, human [MeSH concept]
gene_encodes_gene_product
- LDB3 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Sarcomere [NCIt concept]
- Skeletal Fiber [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
- Scaffolding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- LIM Domain [NCIt concept]
- PDZ Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Myogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients