Leucine-Rich Repeat Serine/Threonine-Protein Kinase 1

Preferred Label : Leucine-Rich Repeat Serine/Threonine-Protein Kinase 1;

NCIt synonyms : LRRK1; EC 2.7.11.1; Leucine Rich Repeat Kinase 1; Leucine-Rich Repeat Kinase 1;

NCIt definition : Leucine-rich repeat serine/threonine-protein kinase 1 (2015 aa, 225 kDa) is encoded by the human LRRK1 gene. This protein is involved in serine/threonine phosphorylation and osteoclast resorption of bone.;

Details

Origin ID

C185556;

UMLS CUI

C1722213;

OMIM relation
- Leucine-rich repeat kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LRRK1 protein, human [MeSH Supplementary Concept]
- LRRK1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- LRRK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Bone Remodeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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