Phosphatidylinositol 4-Phosphate 5-Kinase Type-1 Alpha

Preferred Label : Phosphatidylinositol 4-Phosphate 5-Kinase Type-1 Alpha;

NCIt synonyms : Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha; Phosphatidylinositol 4-Phosphate 5-Kinase Type I Alpha; EC 2.7.1.68; PIP5K1-Alpha; PtdIns(4)P-5-Kinase 1 Alpha; PIP5K1A; PIP5KIalpha; 68 kDa Type I Phosphatidylinositol 4-Phosphate 5-Kinase Alpha;

NCIt definition : Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (562 aa, 63 kDa) is encoded by the human PIP5K1A gene. This protein is involved in the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2).;

Details

Origin ID

C181662;

UMLS CUI

C1679773;

Automatic exact mappings (from CISMeF team)
- Phosphatidylinositol 4-phosphate 5-kinase, type I, alpha [OMIM gene]
- phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [HGNC gene]
OMIM relation
- Phosphatidylinositol 4-phosphate 5-kinase, type I, alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PIP5K1A protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PIP5K1A Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arf1 Signaling Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- E-Cadherin Signaling Pathway in Keratinocytes [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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