DNA Polymerase Beta

Preferred Label : DNA Polymerase Beta;

NCIt synonyms : Beta DNA polymerase; EC 4.2.99.-; EC 2.7.7.7; POLB;

NCIt definition : DNA polymerase beta (335 aa, 38 kDa) is encoded by the human POLB gene. This protein plays a role in both DNA replication and base excision repair.;

NCIt note : DNA polymerase beta has both nucleotidyltransferase and lyase activities.;

Details

Origin ID

C18023;

UMLS CUI

C3853653;

OMIM relation
- Polymerase, dna, beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- POLB protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- POLB Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- DNA Maintenance [NCIt concept]
- DNA Recombination Process [NCIt concept]
- DNA Replication [NCIt concept]
- DNA Synthesis [NCIt concept]
- Drug Resistance Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]

Keyword's position in hierarchy(ies) :

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