Dual Specificity Protein Kinase TTK

Preferred Label : Dual Specificity Protein Kinase TTK;

NCIt synonyms : Cancer/Testis Antigen 96; Phosphotyrosine Picked Threonine-Protein Kinase; Phosphotyrosine-Picked Threonine Kinase; PYT; Monopolar Spindle 1 Homolog; TTK Protein Kinase; TTK; Phosphotyrosine Picked Threonine Kinase; EC 2.7.12.1;

NCIt definition : Dual specificity protein kinase TTK (857 aa, 97 kDa) is encoded by the human TTK gene. This protein is involved in mitotic checkpoint regulation.;

Details

Origin ID

C30147;

UMLS CUI

C1336689;

OMIM relation
- Ttk protein kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- TTK Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Division Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Chromosome Segregation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Luvixasertib [NCIt concept]
- MPS1 Inhibitor [NCIt concept]
- MPS1 Kinase Inhibitor NMS-01940153E [NCIt concept]
- Mps1 Inhibitor BAY 1217389 [NCIt concept]
- Mps1 Inhibitor BOS172722 [NCIt concept]

Keyword's position in hierarchy(ies) :

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