Protein Kinase C Beta Type

Preferred Label : Protein Kinase C Beta Type;

NCIt synonyms : PRKCB1; Protein Kinase C Beta 1; PKCB; EC 2.7.11.13; PKC-B; Protein Kinase C-Beta 1; PKC-Beta; PRKCB; Protein Kinase C Beta, Polypeptide 1;

NCIt definition : Protein kinase C beta type (671 aa, 77 kDa) is encoded by the human PRKCB gene. This protein plays a role in protein phosphorylation, lipid-mediated signaling, apoptosis and cell proliferation.;

Details

Origin ID

C42733;

UMLS CUI

C3710929;

Automatic exact mappings (from CISMeF team)
- Protein kinase C, beta [OMIM gene]
- protein kinase C activity [GO term]
- protein kinase C beta [MeSH Descriptor]
OMIM relation
- Protein kinase C, beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PRKCB protein, human [MeSH concept]
- PRKCB protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PRKCB Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- DAG/PE-Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Ion Channel and Phorbal Esters Signaling Pathway [NCIt concept]
- JNK Signaling in the CD4+ TCR Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Ras Signaling in the CD4+ TCR Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- Vibrio cholerae Infection Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Protein Kinase C [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- PKC-beta Inhibitor MS-553 [NCIt concept]

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