protein kinase C beta

Preferred Label : protein kinase C beta;

MeSH definition : PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.;

MeSH synonym : PKC(beta);

CISMeF synonym : 1, PKC beta; 2, PKC beta; II, PKC-beta;

MeSH hyponym : protein kinase C beta2; protein kinase C beta1; PKCbeta2; Protein Kinase C-beta(II); PKCBII; PKC-beta II; PKC beta II; Protein Kinase C beta I; Protein Kinase C-beta (II); PKC beta 2; beta 2, PKC; Protein Kinase C beta II; PKCB1; PKC beta 1; beta 1, PKC;

Registry Number MeSH : EC 2.7.11.13;

Is substance : O;

UNII : EC 2.7.11.13;

Details

Origin ID

D064546;

UMLS CUI

C0257291;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- PRKCB wt Allele [NCIt concept]
- Protein Kinase C Beta Type [NCIt concept]
- Protein kinase C, beta [OMIM gene]
- cAMP-Dependent Protein Kinase Catalytic Subunit Beta [NCIt concept]
- protein kinase C beta [HGNC gene]
Record concept(s)
- protein kinase C beta [MeSH concept]
- protein kinase C beta1 [MeSH concept]
- protein kinase C beta2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PRKCB protein, human [MeSH Supplementary Concept]
- Prkcb protein, mouse [MeSH Supplementary Concept]
- Prkcb protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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