Non-Receptor Tyrosine-Protein Kinase TNK1

Preferred Label : Non-Receptor Tyrosine-Protein Kinase TNK1;

NCIt synonyms : TNK1; CD38-Negative Kinase; CD38 Negative Kinase; EC 2.7.10.2; Non-Receptor Tyrosine Kinase 1; Non-Receptor Tyrosine Kinase-1;

NCIt definition : Non-receptor tyrosine-protein kinase TNK1 (666 aa, 72 kDa) is encoded by the human TNK1 gene. This protein plays a role in tyrosine phosphorylation, the negative regulation of cell growth and tumor suppression.;

Details

Origin ID

C30114;

UMLS CUI

C0387990;

Automatic exact mappings (from CISMeF team)
- Tyrosine kinase, nonreceptor, 1 [OMIM gene]
OMIM relation
- Tyrosine kinase, nonreceptor, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TNK1 protein, human [MeSH Supplementary Concept]
- TNK1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- TNK1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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