DNA Polymerase Subunit Gamma-1

Preferred Label : DNA Polymerase Subunit Gamma-1;

NCIt synonyms : POLG; Mitochondrial DNA Polymerase Catalytic Subunit; PolG-Alpha; EC 2.7.7.7;

NCIt definition : DNA polymerase subunit gamma-1 (1239 aa, 140 kDa) is encoded by the human POLG gene. This protein plays a role in mitochondrial DNA replication.;

Details

Origin ID

C143071;

UMLS CUI

C1447764;

Automatic exact mappings (from CISMeF team)
- DNA Polymerase gamma [MeSH Descriptor]
- DNA polymerase gamma, catalytic subunit [ORDO Gene]
- Meningococcal Y [UNVA Disease]
- Plague [ORDO Disease]
- Polymerase, dna, gamma [OMIM gene]
- plague [MeSH Descriptor]
OMIM relation
- Polymerase, dna, gamma [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- POLG protein, human [MeSH Supplementary Concept]
- POLG protein, human [MeSH concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- POLG Gene [NCIt concept]
- POLK Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- 3'-5' Exonuclease [NCIt concept]
- DNA Exonuclease [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]

Keyword's position in hierarchy(ies) :

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