DNA Polymerase gamma

Preferred Label : DNA Polymerase gamma;

MeSH definition : A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE.;

MeSH synonym : Polymerase gamma, DNA; Mitochondrial DNA Polymerase; DNA Polymerase, Mitochondrial; Polymerase, Mitochondrial DNA; PolG-alpha; PolG alpha; DNA Polymerase Subunit gamma-1; DNA Polymerase Subunit gamma 1;

Registry Number MeSH : EC 2.7.7.7;

UNII : EC 2.7.7.7;

Details

Origin ID

D000074002;

UMLS CUI

C0535678;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA Polymerase Subunit Gamma-1 [NCIt concept]
- DNA-directed DNA polymerase activity [GO term]
- Polymerase, dna, gamma [OMIM gene]
Record concept(s)
- DNA Polymerase gamma [MeSH concept]
Related MeSH Supplementary Concept(s)
- POLG protein, human [MeSH Supplementary Concept]
- Polg-1 protein, C elegans [MeSH Supplementary Concept]
- polg protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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