Glycerate Kinase

Preferred Label : Glycerate Kinase;

NCIt synonyms : HBeAg Binding Protein 4; EC 2.7.1.31; HBeAg-Binding Protein 4; GLYCTK;

NCIt definition : Glycerate kinase (523 aa, 55 kDa) is encoded by the human GLYCTK gene. This protein plays a role in the conversion of D-glycerate to 3-phosphoglycerate.;

NCIt note : At least 7 isoforms of glycerate kinase are produced by alternative splicing including isoform 2 (GLYCTK2), which is composed of 234 amino acids ( 25 kDa). GLYCTK2 is the product of a variant transcript that is lacking exon 4 and is localized to the mitochondrial matrix as well as the cytoplasm. (OMIM and UniProt);

NCI Metathesaurus CUI : CL1920905;

Details

Origin ID

C201686;

UMLS CUI

C5889833;

OMIM relation
- Glycerate kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GLYCTK Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Mitochondrion [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycerolipid Metabolism Pathway [NCIt concept]
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
- Glyoxylate and Dicarboxylate Metabolism Pathway [NCIt concept]
- Pentose Phosphate Cycle Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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