Rho-Associated Protein Kinase 1

Preferred Label : Rho-Associated Protein Kinase 1;

NCIt synonyms : p160ROCK; ROCK1; Rho-Associated, Coiled-Coil-Containing Protein Kinase I; p160-ROCK; ROCK-I; p160 ROCK-1; Renal Carcinoma Antigen NY-REN-35; Rho-Associated, Coiled-Coil Containing Protein Kinase 1; EC 2.7.11.1; ROCK1 Protein; RHO Kinase;

NCIt definition : Rho-associated protein kinase 1 (1354 aa, 158 kDa) is encoded by the human ROCK1 gene. This protein is involved in both the propagation of Rho signaling and protein phosphorylation.;

Details

Origin ID

C29877;

UMLS CUI

C1335632;

OMIM relation
- Rho-associated coiled-coil-containing protein kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ROCK1 protein, human [MeSH concept]
- ROCK1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- ROCK1 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Stabilization Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Ephrin A Forward Signaling Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Myosin Phosphatase Pathway [NCIt concept]
- Noncanonical Wnt Signaling Pathway [NCIt concept]
- PTP4A Family Signaling Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- Thrombin/Protease-Activated Receptor Signaling Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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