Nucleoside Diphosphate Kinase A

Preferred Label : Nucleoside Diphosphate Kinase A;

NCIt synonyms : p19-NM23; EC 2.7.4.6; Metastasis Inhibition Factor NM23; NM23 Gene Product; NDKA; NDP Kinase A; nm23-H1; Granzyme A-Activated DNase; Tumor Metastatic Process-Associated Protein; GAAD; NDK A; Nucleoside Diphosphate Kinase-A; NME1;

NCIt definition : Nucleoside diphosphate kinase A (152 aa, 17 kDa) is encoded by the human NME1 gene. This protein plays a role in nucleoside triphosphate synthesis, lipid and protein phosphorylation, apoptosis and the regulation of cell proliferation.;

Details

Origin ID

C17314;

UMLS CUI

C1504701;

OMIM relation
- Nme/nm23 nucleoside diphosphate kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NME1 protein, human [MeSH Supplementary Concept]
- NME1 protein, human [MeSH concept]
- nucleoside diphosphate kinase A [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NME1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adherens Junction Formation Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- Arf6 Trafficking Pathway [NCIt concept]
- Granzyme A Mediated Apoptosis Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
- Synaptic Vesicle Endocytosis Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Neuroblastoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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