Serine/Threonine-Protein Kinase PAK 3

Preferred Label : Serine/Threonine-Protein Kinase PAK 3;

NCIt synonyms : p21 CDC42/RAC1-Activated Kinase 3; p21-Activated Kinase-3; EC 2.7.11.1; Oligophrenin-3; Beta-PAK; p21-Activated Protein Kinase 3; PAK-3; p21-Activated Kinase 3; Oligophrenin 3; PAK3beta; PAK3;

NCIt definition : Serine/threonine-protein kinase PAK 3 (559 aa, 62 kDa) is encoded by the human PAK3 gene. This protein is involved in the phosphorylation-dependent modulation of signal transduction.;

Details

Origin ID

C127851;

UMLS CUI

C1568884;

Automatic exact mappings (from CISMeF team)
- P21 protein-activated kinase 3 [OMIM gene]
- p21 (RAC1) activated kinase 3 [ORDO Gene]
- p21-Activated kinase 3 [MeSH concept]
- p21-Activated kinases [MeSH Descriptor]
OMIM relation
- P21 protein-activated kinase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PAK3 protein, human [MeSH Supplementary Concept]
- PAK3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PAK3 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Nervous System [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Agrin Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Migration Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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