TRAF2 and NCK-Interacting Protein Kinase

Preferred Label : TRAF2 and NCK-Interacting Protein Kinase;

NCIt synonyms : TRAF2- and NCK- Interacting Kinase; EC 2.7.11.1; TRAF2 and NCK Interacting Kinase; TNIK;

NCIt definition : TRAF2 and NCK-interacting protein kinase (1360 aa, 155 kDa) is encoded by the human TNIK gene. This protein plays a role in Wnt signaling pathway regulation and protein phosphorylation.;

NCI Metathesaurus CUI : CL981390;

Details

Origin ID

C185559;

UMLS CUI

C1449299;

Automatic exact mappings (from CISMeF team)
- TRAF2 and NCK interacting kinase [ORDO Gene]
- TRAF2 and NCK interacting kinase [HGNC gene]
- Traf2- and nck-interacting kinase [OMIM gene]
OMIM relation
- Traf2- and nck-interacting kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TNIK protein, human [MeSH Supplementary Concept]
- TNIK protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- TNIK Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Cytoskeleton [NCIt concept]
- Endosome [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Induction [NCIt concept]

Keyword's position in hierarchy(ies) :

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